Due to breeding for performance, retired racing Greyhounds are a relatively healthy breed. They are not prone to hip dysplasia or other problems like some breeds of similar size. The more common problems seen in the breed are hypothyroidism, arthritis in older dogs, and periodontal disease.

Their teeth are prone to tartar build up and need regular brushing that you can do at home, or dental cleanings that your vet will perform under anesthesia. Some Greyhounds have beautiful teeth and never need a dental; others need dentals as often as once a year. Chewing bones can also help to scrape tartar from the teeth.